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老年人C-2骨折模式:特定骨折类型的病因、治疗及死亡率比较

Patterns of C-2 fracture in the elderly: comparison of etiology, treatment, and mortality among specific fracture types.

作者信息

Radovanovic Ingrid, Urquhart Jennifer C, Rasoulinejad Parham, Gurr Kevin R, Siddiqi Fawaz, Bailey Christopher S

机构信息

Division of Orthopaedics, Department of Surgery, Schulich School of Medicine and Dentistry, The University of Western Ontario.

London Health Sciences Center, London, Ontario, Canada.

出版信息

J Neurosurg Spine. 2017 Nov;27(5):494-500. doi: 10.3171/2017.3.SPINE161176. Epub 2017 Aug 18.

Abstract

OBJECTIVE Previous studies have focused on Type II odontoid fractures and have failed to report on the effect of other C-2 fracture types on treatment and outcome. The purpose of this study was to compare patient characteristics, cause of injury, predisposing factors to fracture, treatments, and mortality rates among C-2 fracture types in a cohort of elderly patients 70 years of age and older. METHODS A retrospective cohort study design was used. Patients who sustained a C-2 fracture between 2002 and 2011 and who were admitted to the authors' Level 1 trauma center were identified using the Discharge Abstract Database and the International Statistical Classification of Diseases and Related Health Problems (ICD-10) code S12.1. Fractures were classified as odontoid Type I, II, or III; hangman's; C-2 complex (hangman's appearance on sagittal images, Type III odontoid on coronal cuts); and other (miscellaneous). Age, sex, predisposing factors to falls, cause of injury, treatment, presence of autofusion in the subaxial cervical spine, and mortality rates were compared between fracture patterns. RESULTS One hundred forty-one patients were included; their mean age was 82 years. Fractures included Type II odontoid (57%), complex (19%), Type III odontoid (11%), hangman's (8%), and other (5%). Falls from a standing height accounted for 47% of injuries, and 65% of patients had ≥ 3 risk factors for falls. Subaxial autofusion was more common in odontoid fractures (p = 0.002). Treatment was mainly nonoperative (p < 0.0001). The 1-year mortality rate was 27%. Four patients died of spinal cord injury. CONCLUSIONS Although not as common as Type II odontoid fractures, other C-2 fractures including hangman's, complex, and Type III odontoid fractures accounted for close to half of the injuries in the study cohort. There were few differences between the fracture types with respect to cause of injury, predisposing factors, or mortality rate. However, surgical treatment was more common for Type II odontoid fractures.

摘要

目的 以往研究主要聚焦于Ⅱ型齿状突骨折,而未报告其他C2骨折类型对治疗及预后的影响。本研究旨在比较70岁及以上老年患者队列中不同C2骨折类型的患者特征、损伤原因、骨折诱发因素、治疗方法及死亡率。方法 采用回顾性队列研究设计。利用出院摘要数据库和国际疾病及相关健康问题统计分类(ICD-10)编码S12.1,确定2002年至2011年间在作者所在的一级创伤中心住院的C2骨折患者。骨折分为齿状突Ⅰ型、Ⅱ型或Ⅲ型;绞刑者骨折;C2复合体骨折(矢状位图像呈绞刑者外观,冠状位切面为Ⅲ型齿状突骨折);以及其他(杂类)骨折。比较不同骨折类型之间的年龄、性别、跌倒诱发因素、损伤原因、治疗方法、下颈椎自体融合情况及死亡率。结果 共纳入141例患者,平均年龄82岁。骨折类型包括Ⅱ型齿状突骨折(57%)、复合体骨折(19%)、Ⅲ型齿状突骨折(11%)、绞刑者骨折(8%)及其他骨折(5%)。站立位跌倒导致的损伤占47%,65%的患者有≥3项跌倒风险因素。下颈椎自体融合在齿状突骨折中更为常见(p = 0.002)。治疗主要为非手术治疗(p < 0.0001)。1年死亡率为27%。4例患者死于脊髓损伤。结论 尽管不像Ⅱ型齿状突骨折那样常见,但包括绞刑者骨折、复合体骨折及Ⅲ型齿状突骨折在内的其他C2骨折在研究队列中占损伤近一半。不同骨折类型在损伤原因、诱发因素或死亡率方面差异不大。然而,Ⅱ型齿状突骨折手术治疗更为常见。

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