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[Metipranolol 0.1% and pilocarpine 2% as a fixed combination compared to each substance alone in the treatment of glaucoma. A controlled, randomized clinical study comparing the intraindividual effects and tolerance].

作者信息

Scharrer A, Ober M

出版信息

Klin Monbl Augenheilkd. 1986 Dec;189(6):450-5. doi: 10.1055/s-2008-1050851.

DOI:10.1055/s-2008-1050851
PMID:2882046
Abstract

A fixed combination of pilocarpine 2% and metipranolol 0.1% was found to have a better pressure-lowering effect than pilocarpine 2% alone or metipranolol 0.1% alone, as well as being tolerated well, both subjectively and objectively. In many cases only the fixed combination was successful in lowering intraocular pressure to tolerable values.

摘要

相似文献

1
[Metipranolol 0.1% and pilocarpine 2% as a fixed combination compared to each substance alone in the treatment of glaucoma. A controlled, randomized clinical study comparing the intraindividual effects and tolerance].
Klin Monbl Augenheilkd. 1986 Dec;189(6):450-5. doi: 10.1055/s-2008-1050851.
2
[Effectiveness and tolerance of metipranolol--results of a multi-center long-term study in Switzerland].美替洛尔的有效性和耐受性——瑞士多中心长期研究结果
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Prepared association of metipranolol 0.1% + pilocarpine 2% and of timolol 0.5% + pilocarpine 2%. Comparison of clinical efficacy and topical tolerability in the treatment of patients affected by POAG tonometrically uncontrolled with beta-blocker alone (two-centre study).制备的0.1%美替洛尔+2%毛果芸香碱以及0.5%噻吗洛尔+2%毛果芸香碱组合。在眼压未得到控制的原发性开角型青光眼患者中单独使用β受体阻滞剂治疗的临床疗效和局部耐受性比较(双中心研究)
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[Effect of various beta blockers on intraocular pressure and ventilation].
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[Metipranolol 0.1%: effect of a single dose on the nycthemeral pressure curve in an eye with chronic primary open-angle glaucoma].[美替洛尔0.1%:单剂量对慢性原发性开角型青光眼患眼昼夜眼压曲线的影响]
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7
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Intraocular pressure-lowering effects of latanoprost monotherapy versus latanoprost or pilocarpine in combination with timolol: a randomized, observer-masked multicenter study in patients with open-angle glaucoma. Italian Latanoprost Study Group.拉坦前列素单药治疗与拉坦前列素或毛果芸香碱联合噻吗洛尔降低眼压的效果比较:一项针对开角型青光眼患者的随机、观察者盲法多中心研究。意大利拉坦前列素研究组
J Glaucoma. 1999 Feb;8(1):24-30.

引用本文的文献

1
Management of glaucoma: focus on pharmacological therapy.青光眼的治疗:聚焦于药物治疗。
Drugs Aging. 2005;22(1):1-21. doi: 10.2165/00002512-200522010-00001.
2
Pharmacological therapy for glaucoma: a review.青光眼的药物治疗:综述
Drugs. 2000 Mar;59(3):411-34. doi: 10.2165/00003495-200059030-00003.
3
Ocular metipranolol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in glaucoma and ocular hypertension.眼部用美替洛尔。其药效学和药代动力学特性以及在青光眼和高眼压症治疗效果的初步综述。
Drugs. 1988 Nov;36(5):601-15. doi: 10.2165/00003495-198836050-00004.