Scharrer A, Ober M
Klin Monbl Augenheilkd. 1986 Dec;189(6):450-5. doi: 10.1055/s-2008-1050851.
A fixed combination of pilocarpine 2% and metipranolol 0.1% was found to have a better pressure-lowering effect than pilocarpine 2% alone or metipranolol 0.1% alone, as well as being tolerated well, both subjectively and objectively. In many cases only the fixed combination was successful in lowering intraocular pressure to tolerable values.