Merté H J, Stryz J R, Mertz M
Klin Monbl Augenheilkd. 1983 Apr;182(4):286-9.
In a short-term study the pressure-lowering effects of Metipranolol 0.3% and Timolol 0.25% were compared in eyes with open-angle glaucoma by means of one-drop curves, diurnal pressure curves and tonography. It appears that these two drugs may be regarded as equal in respect of extent and duration of action. Aqueous humor outflow was facilitated slightly by both drugs, although increase was only statistically significant with Metipranolol.
在一项短期研究中,通过单滴曲线、昼夜眼压曲线和眼压描记法,比较了0.3%美替洛尔和0.25%噻吗洛尔对开角型青光眼患者眼睛的降压效果。结果显示,就作用程度和持续时间而言,这两种药物可视为等效。两种药物均轻微促进房水流出,不过仅美替洛尔使房水流出增加具有统计学意义。