Wang Shi-Qi, Duan Ze-Hua, Zhao Ya-Rong, Dou Huan
The State Key Laboratory of Pharmaceutical Biotechnology, Medical School, Nanjing University, Nanjing 210093, China.
Zhongguo Zhong Yao Za Zhi. 2017 Jun;42(11):2042-2045. doi: 10.19540/j.cnki.cjcmm.20170224.006.
Halofuginone (HF) is a derivative of dichroine which is the extract of traditional Chinese medicine. It is widely used as an efficient anticoccidial drug. Recent studies have found that HF has unique biological activities, showing great potential capacities in the treatment of autoimmune diseases. In the article, we summarized the therapeutic effects of HF in a variety of autoimmune diseases and its mechanism, providing references for further clinical studies of HF.