Duan Wen-Juan, Li Yue, Cui Li, Liu Feng, Yang Guo-Hong, Guo Lan-Ping, Wang Xiao
Shandong Key Laboratory of Traditional Chinese Medicine Quality Control Technology, Shandong Analysis and test Center, Ji'nan 250014, China.
National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Zhongguo Zhong Yao Za Zhi. 2017 Jun;42(11):2092-2096. doi: 10.19540/j.cnki.cjcmm.20170415.004.
Moisture status and content during the processing of Paeoniae Radix Alba were studied by nuclear magnetic resonance (NMR) and nuclear magnetic resonance imaging (MRI) to investigate the changes of transverse relaxation time (T ₂) and MRI images during boiling and drying processes of Paeoniae Radix Alba. The results showed that water in Paeoniae Radix Alba fresh products was major of free water, and in the boiling process, the content of free water increased whereas the content of bound water declined. At the end of boiling, content of free water reached over 90%. During the drying process, T ₂ moved to the left, and moisture mobility was reduced. The MRI image directly showed that moisture transfer was outside-in process for both increase and decrease. At the end of drying, remaining moisture was mainly present in inner layer of Paeoniae Radix Alba. Quality and appearance were affected by the change of moisture during processing process of medicinal herbs. NMR and MRI could provide direct reference evidence for its moisture changes, and the results of this study could provide direct references and technical support for optimization of processing process of root medicinal materials and evaluation of Chinese herbal pieces.
采用核磁共振（NMR）和核磁共振成像（MRI）技术研究白芍加工过程中的水分状态和含量，以探讨白芍在水煮和干燥过程中横向弛豫时间（T₂）及MRI图像的变化。结果表明，白芍鲜品中的水分主要为自由水，在水煮过程中，自由水含量增加而结合水含量下降。水煮结束时，自由水含量超过90%。在干燥过程中，T₂向左移动，水分迁移率降低。MRI图像直接显示，水分增加和减少的转移过程均为由外向内。干燥结束时，剩余水分主要存在于白芍内层。药材加工过程中水分的变化会影响其质量和外观。NMR和MRI可为其水分变化提供直接参考依据，本研究结果可为根类药材加工工艺优化及中药饮片评价提供直接参考和技术支持。
