在化脓性肝脓肿和晚期乙状结肠癌中同时检测到具核梭杆菌。
Fusobacterium nucleatum detected simultaneously in a pyogenic liver abscess and advanced sigmoid colon cancer.
作者信息
Shigefuku Ryuta, Watanabe Tsunamasa, Kanno Yuki, Ikeda Hiroki, Nakano Hiroyasu, Hattori Nobuhiro, Matsunaga Kotaro, Matsumoto Nobuyuki, Kanno Shin-Ichi, Nosho Katsuhiko, Hachiya Atsuko, Iwatani Yasumasa, Matsumori Tomoko, Tsukikawa Satoshi, Makizumi Ryoji, Otsubo Takehito, Yamamoto Hiroyuki, Itoh Fumio
机构信息
Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
Department of Gastroenterology, Sapporo Medical University School of Medicine, Japan.
出版信息
Anaerobe. 2017 Dec;48:144-146. doi: 10.1016/j.anaerobe.2017.08.010. Epub 2017 Aug 16.
Fusobacterium nucleatum is an invasive, adherent, and pro-inflammatory anaerobic bacterium involved in various infections and colorectal cancer. We report a case with pyogenic liver abscess, diagnosed with advanced sigmoid colon cancer, in whom F. nucleatum was simultaneously detected. In this patient, F. nucleatum was systematically analyzed using the molecular biological techniques of metagenome analysis, conventional PCR, and microbial fluorescence in situ hybridization.
具核梭杆菌是一种具有侵袭性、粘附性且促炎的厌氧菌，与多种感染及结直肠癌有关。我们报告了一例患有化脓性肝脓肿且被诊断为晚期乙状结肠癌的病例，该病例同时检测到具核梭杆菌。在该患者中，运用宏基因组分析、常规聚合酶链反应及微生物荧光原位杂交等分子生物学技术对具核梭杆菌进行了系统分析。
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