Department of Internal Medicine, Hitachiomiya Saiseikai Hospital, 3033-3 Tagouchi-cho, Ibaraki, 319-2256, Japan.
Department of Surgery, Hitachiomiya Saiseikai Hospital, Ibaraki, Japan.
Clin J Gastroenterol. 2021 Apr;14(2):617-620. doi: 10.1007/s12328-021-01376-9. Epub 2021 Mar 6.
Pyogenic liver abscesses generally occur secondary to spread from active infective lesions. We report a rare case of liver abscess in a patient without a clear source of infection. A 19-year-old man was diagnosed as having a liver abscess after investigations when he presented with chief complaints of fever and lethargy. Fusobacterium nucleatum was detected in the pus culture taken from the abscess that was drained. His condition improved with antibacterial treatment. Further examination of the gastrointestinal tract suggested that the infection had tracked through the portal vein from a scar between the rectal sigmoid and the appendix. Laparoscopic adhesiolysis and appendectomy were performed to treat the same. Fusobacterium can be identified early by Gram staining of pus from the liver abscess, which is useful for treatment. In young people with pyogenic liver abscess due to Fusobacterium nucleatum who are not immunocompromised, examination of the gastrointestinal tract should be considered to determine a cause.
化脓性肝脓肿通常继发于活跃感染病灶的播散。我们报告了一例罕见的无明确感染源的肝脓肿病例。一名 19 岁男性因发热和乏力就诊,经检查诊断为肝脓肿。从引流的脓肿中检出核梭杆菌。经抗菌治疗后,患者病情好转。进一步检查胃肠道提示感染经门静脉从直肠乙状结肠和阑尾之间的疤痕处追踪而来。行腹腔镜粘连松解术和阑尾切除术治疗。通过对肝脓肿脓液进行革兰氏染色可以早期识别出梭杆菌,这对治疗很有帮助。对于因核梭杆菌引起的化脓性肝脓肿且无免疫功能低下的年轻患者,应考虑检查胃肠道以确定病因。