Lee E H, Huang S L, Chai C Y
Life Sci. 1987 Apr 6;40(14):1431-7. doi: 10.1016/0024-3205(87)90334-1.
Effects of amphetamine on concentrations of dopamine, norepinephrine and serotonin in several monoamine-containing cell body and terminal regions were examined left and right separately in rats. Results suggest that amphetamine reduced the L-R asymmetry of most of these measures, and this effect is more significant in the cell body than in the terminal regions. Behaviorally, amphetamine also decreased L-R asymmetry of the spontaneous turning behavior in rats and this latter effect is most closely associated with the reductions of dopamine and norepinephrine asymmetries in the substantia nigra and reduction of norepinephrine asymmetry in the locus coeruleus.
在大鼠中，分别对左右两侧进行了研究，考察了苯丙胺对几个含单胺的细胞体和终末区域中多巴胺、去甲肾上腺素和5-羟色胺浓度的影响。结果表明，苯丙胺降低了这些指标中大多数的左右不对称性，且这种作用在细胞体中比在终末区域更显著。在行为方面，苯丙胺也降低了大鼠自发旋转行为的左右不对称性，而后一种作用与黑质中多巴胺和去甲肾上腺素不对称性的降低以及蓝斑中去甲肾上腺素不对称性的降低最为密切相关。
