Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
State Key Laboratory of Elemento-Organic Chemistry, Nankai University , Tianjin 300071, China.
Org Lett. 2017 Sep 1;19(17):4540-4543. doi: 10.1021/acs.orglett.7b02121. Epub 2017 Aug 21.
An efficient CuCl/EtN-catalyzed tandem reaction for the synthesis of indanone-fused pyrrolidine was developed. In this process, two rings and four bonds are generated in one pot with high atom-economy and step-efficiency. The addition of EtN was found as the key factor for the success of the tandem reaction.
一种高效的 CuCl/EtN 催化串联反应被开发用于合成茚酮并吡咯烷。在这个过程中，一锅法中生成了两个环和四个键，具有高原子经济性和步骤效率。发现添加 EtN 是串联反应成功的关键因素。
