Rizzo Leonardo F L, Mana Daniela L, Bruno Oscar D, Wartofsky Leonard
Dirección Médica Química Montpellier SA, Buenos Aires, Argentina.
Dirección Médica Química Montpellier SA, Buenos Aires, Argentina. E-mail:
Medicina (B Aires). 2017;77(4):321-328.
Hypothyroidism is a frequently diagnosed and simply treated disease. If not recognised, however, in time it may develop into the most severe manifestation of hypothyroidism known as myxedema coma. The term "myxedema coma" is generally seen as misleading since most patients do not initially present in a coma. The typical progression is lethargy evolving into stupor and, eventually, into coma with respiratory failure and hypothermia. It mainly affects elderly women, often occurring in winter and is relatively rare. It can be considered a form of decompensated hypothyroidism often triggered by a variety of non-thyroid conditions or diseases provoking an extremely severe condition of multiple system failure with lethal consequences unless an early diagnosis is made and an aggressive treatment is administered.
甲状腺功能减退症是一种常被诊断且易于治疗的疾病。然而，如果未能及时识别，它可能发展为甲状腺功能减退症最严重的表现形式，即黏液性水肿昏迷。“黏液性水肿昏迷”这个术语通常被认为具有误导性，因为大多数患者最初并非处于昏迷状态。典型的病程是从嗜睡发展为昏迷，最终发展为伴有呼吸衰竭和体温过低的昏迷。它主要影响老年女性，常在冬季发生，且相对罕见。它可被视为一种失代偿性甲状腺功能减退症，通常由多种非甲状腺疾病引发，导致极其严重的多系统功能衰竭状态，若不进行早期诊断和积极治疗，会产生致命后果。
