Jiaxing University Master Degree Cultivation Base, Zhejiang Chinese Medical University, Hangzhou, China.
Department of Anesthesiology, The Second Affiliated Hospital of Jiaxing University, Jiaxing, China.
J Int Med Res. 2023 Sep;51(9):3000605231197947. doi: 10.1177/03000605231197947.
Myxedema coma is a rare and life-threatening endocrine emergency characterized by abnormalities in multiple organ systems. A 32-year-old woman with prolonged undiagnosed severe hypothyroidism was referred to our hospital owing to lower abdominal pain and menopause for more than 3 months. She underwent exploratory laparotomy and induced abortion under general anesthesia, and developed severe hypoxemia after extubation. She was diagnosed with myxedema coma, and was subsequently discharged with a good prognosis following treatment. This case suggests that myxedema coma should be considered a potential etiology of peri-operative hypoxemia. The findings in this case emphasize the importance of anesthesiologists' comprehensive understanding of myxedema coma. Prompt diagnosis followed by treatment is essential to reduce the mortality rate associated with this condition.
黏液性水肿昏迷是一种罕见且危及生命的内分泌急症,其特征为多个器官系统异常。一名 32 岁女性因下腹疼痛和绝经 3 个月以上被转入我院。她在全身麻醉下接受了剖腹探查术和人工流产,拔管后出现严重低氧血症。诊断为黏液性水肿昏迷,经治疗后预后良好出院。本例提示,黏液性水肿昏迷应考虑为围手术期低氧血症的潜在病因。该病例的发现强调了麻醉师全面了解黏液性水肿昏迷的重要性。及时诊断和治疗对于降低该疾病相关死亡率至关重要。