Minderaa R B
Tijdschr Kindergeneeskd. 1987 Feb;55(1):10-5.
Tourette syndrome is a neuropsychiatric disorder of motor and vocal tics, with associated symptoms of obsessive-compulsive behaviors and attention deficit disorder with hyperactivity. Genetic factors seem to play a major role, but the precise mode of inheritance is still not known. Intervention includes reassurance and support of child and family, medication if needed and guidance and advocacy in relation to school achievements. The major goal of treatment is to help the child succeed in moving along the various lines of development. Clonidine, a centrally active alpha2-noradrenergic agonist is the first choice of medical treatment in most cases. If clonidine fails, pimozide and haloperidol are considered to be good alternatives.
抽动秽语综合征是一种伴有运动和发声抽动的神经精神障碍,还伴有强迫行为和注意力缺陷多动障碍等相关症状。遗传因素似乎起主要作用,但确切的遗传模式仍不清楚。干预措施包括安抚和支持患儿及其家庭,必要时用药,以及在学业成绩方面提供指导和支持。治疗的主要目标是帮助患儿在各个发展阶段取得成功。可乐定,一种中枢活性α2-去甲肾上腺素能激动剂,在大多数情况下是药物治疗的首选。如果可乐定治疗失败,匹莫齐特和氟哌啶醇被认为是不错的替代药物。