Psychiatric Clinic,414 Military Hospital of Athens,P. Penteli,Greece.
Department of Biostatistics,Institute of Psychiatry, Psychology and Neuroscience, King's College London,London,UK.
Psychol Med. 2018 Apr;48(5):728-736. doi: 10.1017/S0033291717002276. Epub 2017 Aug 22.
Since the seminal study of Steinbeck and Durell (1968), few epidemiological studies have attempted to replicate whether psychosocial stress precipitates the onset of a first psychotic episode. Our aim was to support or refute the finding of elevated psychosis incidence in the first month of army induction and to examine factors impacting the timing of onset. Data were collected from medical files of 186 army conscripts, hospitalized with a diagnosis of First Episode Psychosis (FEP) between 2005 and 2014 in the Psychiatric Military Hospital in Athens, Greece. FEP rates were at least 4.5 times higher in the first month of military service, compared with any other month. Earlier FEP onset was associated with rural environment at the time of birth, multiple drug use and service away from home. Psychosocial stress precipitates FEP, particularly in those exposed to other risk factors.
自 Steinbeck 和 Durell（1968 年）的开创性研究以来，很少有流行病学研究试图复制心理社会压力是否会引发首次精神病发作。我们的目的是支持或反驳在入伍的第一个月中精神病发病率升高的发现，并研究影响发病时间的因素。数据来自于希腊雅典精神病军事医院 2005 年至 2014 年间因首次发作性精神病（FEP）住院的 186 名应征入伍者的病历。与其他任何一个月相比，在服兵役的第一个月中，FEP 的发病率至少高出 4.5 倍。更早的 FEP 发病与出生时的农村环境、多种药物使用和离家服务有关。心理社会压力会引发 FEP，尤其是在那些同时暴露于其他风险因素的人群中。
