Fehér E, Léránth C, Gallatz K
Acta Morphol Hung. 1986;34(1-2):59-71.
Somatostatin-containing nerve elements were identified by light and electron microscopic immunocytochemistry in the rat small intestine. Labelled nerve cell bodies were found in the submucous plexus. In the myenteric plexus and the mucosa, numerous somatostatin positive fibers were found. Labelled fibers were observed in the vicinity of blood vessels, close to the smooth muscle cell membrane and to the lamina basalis of epithelial cells. In both plexuses, there were many synapses between the labelled and unlabelled nerve elements. After transection of the nn. mesenteric some of the degenerated nerve fibers originating outside the wall of the small intestine contained also somatostatin immunoreactivity. These observations suggest that somatostatin nerves not only influence the blood flow, but participate in regulation of smooth muscle activity and, by the aid of their interneuronal synapses they have a regulatory or transmitter effect on the other intrinsic nerve elements.
通过光镜和电镜免疫细胞化学方法在大鼠小肠中鉴定出含生长抑素的神经成分。在黏膜下神经丛中发现了标记的神经细胞体。在肌间神经丛和黏膜中，发现了大量生长抑素阳性纤维。在血管附近、靠近平滑肌细胞膜和上皮细胞基膜处观察到标记纤维。在两个神经丛中，标记和未标记的神经成分之间存在许多突触。在肠系膜神经切断后，一些起源于小肠壁外的变性神经纤维也含有生长抑素免疫反应性。这些观察结果表明，生长抑素神经不仅影响血流，还参与平滑肌活动的调节，并且借助其神经元间突触对其他内在神经成分具有调节或传递作用。
