Sahay Pranita, Saluja Gunjan, Maharana Prafulla Kumar, Titiyal Jeewan S
Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
BMJ Case Rep. 2017 Aug 20;2017:bcr-2017-220739. doi: 10.1136/bcr-2017-220739.
A 40-years-old female patient was referred to the cornea clinic as a probable case of bilateral keratitis. The patient had a history of headache followed by acute onset of redness, pain and discharge from both eyes for 15 days. The patient was diagnosed as bilateral keratitis by the first contact physician and was started on topical antibiotics, cycloplegics and lubricating eye-drops. At presentation, both eyes had visual acuity of perception of light, conjunctival congestion, limbal blanching, diffuse corneal oedema and epithelial defect. A detailed history revealed application of Vicks VapoRub [topical ayurvedic analgesic which contains (per 100 g of product) menthol (2.82 g), camphor (5.25 g) and eucalyptol (1.49 mL) and excipients include thymol (0.1 g), turpentine oil (5.57 mL), nutmeg oil (0.54 mL), cedar wood oil and petrolatum)] on the forehead and eyelids for headache several times over 2-3 days before the onset. The patient further confirmed the accidental application of the ointment in the eyes. A provisional diagnosis of acute chemical injury with Vicks VapoRub was made and treatment with topical antibiotic, cycloplegic, steroid, lubricant and vitamin C was started. On follow-up, both eyes showed gradual resolution of corneal oedema and epithelial defect. Visual acuity improved in the left eye to 6/60 with no change in right eye due to corneal haze.
一名40岁女性患者因疑似双侧角膜炎被转诊至角膜门诊。患者有头痛病史,随后双眼急性发红、疼痛并伴有分泌物,持续15天。首诊医生诊断为双侧角膜炎,并开始使用局部抗生素、睫状肌麻痹剂和润滑眼药水治疗。就诊时,双眼视力仅为光感,结膜充血,角膜缘苍白,角膜弥漫性水肿及上皮缺损。详细病史显示,在发病前2 - 3天,患者曾多次为缓解头痛在前额和眼睑涂抹维克斯达姆膏(一种阿育吠陀局部止痛膏,每100克产品含薄荷醇2.82克、樟脑5.25克、桉叶油1.49毫升,辅料包括百里酚0.1克、松节油5.57毫升、肉豆蔻油0.54毫升、雪松木油和凡士林)。患者进一步证实曾意外将该药膏涂入眼内。初步诊断为维克斯达姆膏所致急性化学伤,并开始使用局部抗生素、睫状肌麻痹剂、类固醇、润滑剂和维生素C进行治疗。在随访过程中,双眼角膜水肿和上皮缺损逐渐消退。左眼视力提高到6/60,右眼因角膜混浊视力无变化。