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伴有环形浸润的双侧真菌性角膜炎:一种罕见情况。

Bilateral fungal keratitis with ring infiltrates: a rare scenario.

作者信息

Chaniyara Manthan Hasmukhbhai, Pujari Amar, Urkude Jayanand, Sharma Namrata

机构信息

Dr Rajendra Prasad Centre for Ophthalmic Sciences, All IndiaInstitute of Medical Sciences, New Delhi, India.

出版信息

BMJ Case Rep. 2017 Oct 9;2017:bcr-2017-221226. doi: 10.1136/bcr-2017-221226.

DOI:10.1136/bcr-2017-221226
PMID:28993355
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5652377/
Abstract

A 12-year-old boy presented to the emergency department with chief complaints of pain, redness, discharge and diminution of vision in both eyes over the previous 20 days. There was no history of preceding trauma, contact lens use, any eye drop usage or ocular surgery. Systemic history was not significant. Presenting uncorrected visual acuity in his right eye was counting fingers at 1 m and 20/200 in the left eye, with accurate projection of rays in both eyes. Slit lamp biomicroscopy showed the presence of bilateral diffuse conjunctival congestion, corneal ring infiltrates and epithelial defect with corneal oedema. Potassium hydroxide wet mount showed the presence of septate fungal hyphae. The patient was treated with topical 5% natamycin and 1% voriconazole over a period of 6 weeks. Best-corrected visual acuity was 20/600 in the right eye and 20/20 in the left eye at 6-month follow-up.

摘要

一名12岁男孩因双眼疼痛、发红、有分泌物及视力下降20天就诊于急诊科。既往无外伤史、未使用过隐形眼镜、未使用过任何眼药水或眼部手术史。全身病史无特殊。就诊时右眼裸眼视力为1米指数,左眼为20/200,双眼光线投射准确。裂隙灯显微镜检查显示双眼弥漫性结膜充血、角膜环形浸润及上皮缺损伴角膜水肿。氢氧化钾湿片检查显示有分隔的真菌菌丝。患者接受了为期6周的局部5%那他霉素和1%伏立康唑治疗。6个月随访时,右眼最佳矫正视力为20/600,左眼为20/20。

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本文引用的文献

1
Analysis of the risk factors predisposing to fungal, bacterial & Acanthamoeba keratitis in south India.分析导致印度南部真菌性、细菌性和棘阿米巴角膜炎的危险因素。
Indian J Med Res. 2009 Dec;130(6):749-57.
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Fungal infections of the cornea.角膜真菌感染
Eye (Lond). 2003 Nov;17(8):852-62. doi: 10.1038/sj.eye.6700557.
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Simultaneous bilateral fungal keratitis caused by different fungi.由不同真菌引起的同时性双侧真菌性角膜炎。
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Therapeutic contact lens-related bilateral fungal keratitis.治疗性隐形眼镜相关的双侧真菌性角膜炎。
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Acanthamoeba keratitis in England and Wales: incidence, outcome, and risk factors.英格兰和威尔士的棘阿米巴角膜炎:发病率、转归及危险因素
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6
Bilateral infectious keratitis after laser in situ keratomileusis: a case report and review of the literature.准分子原位角膜磨镶术后双侧感染性角膜炎:一例报告并文献复习
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Epidemiology and aetiological diagnosis of corneal ulceration in Madurai, south India.印度南部马杜赖角膜溃疡的流行病学及病因诊断
Br J Ophthalmol. 1997 Nov;81(11):965-71. doi: 10.1136/bjo.81.11.965.
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Spectrum of oculomycosis in South India.印度南部眼部真菌病的范围
Acta Ophthalmol (Copenh). 1991 Dec;69(6):744-9. doi: 10.1111/j.1755-3768.1991.tb02053.x.
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Fungal keratitis.真菌性角膜炎
Infect Dis Clin North Am. 1992 Dec;6(4):851-7.