Craven J L, Voore P M, Voineskos G
Can J Psychiatry. 1987 Apr;32(3):199-203. doi: 10.1177/070674378703200308.
Little is known about the extent of the use of prn psychotropic medication in psychiatric inpatient units. A survey of the prn prescription and administration of psychotropic drugs in a psychiatric teaching hospital revealed that a large number of inpatients were prescribed and administered such drugs on a prn basis. Although 50% of the prescriptions were never administered, only 25% were actively discontinued by physicians. A diagnosis of personality disorder was the factor most frequently associated with the rate of prn prescriptions and of administrations. A large number of prn prescriptions had no instructions for indications, minimum time spacing between doses or maximum daily dosage. It is suggested that hospitals monitor the prn use of psychotropic medications in their inpatient units, and explore the reasons for such use. Psychotropic drug use on a prn basis should preferably be reserved for emergencies, and the instructions of prn prescriptions should be clear and detailed.
关于精神科住院病房按需使用精神药物的情况，人们了解甚少。一项对某精神科教学医院精神药物按需处方及用药情况的调查显示，大量住院患者按按需原则被处方并使用此类药物。尽管50%的处方从未被使用，但只有25%被医生主动停用。人格障碍诊断是与按需处方率和用药率最常相关的因素。大量按需处方没有关于适应证、剂量之间的最短时间间隔或最大日剂量的说明。建议医院监测其住院病房中精神药物的按需使用情况，并探究此类使用的原因。按需使用精神药物最好应仅限于紧急情况，且按需处方的说明应清晰详细。
