1Department of Surgery,University of Alberta,Alberta,Canada.
2Department of Anaesthesia,University of Alberta,Alberta,Canada.
Can J Neurol Sci. 2017 Nov;44(6):692-696. doi: 10.1017/cjn.2017.210. Epub 2017 Aug 22.
Cross-clamp ischemia during carotid endarterectomy can be prevented with carotid bypass shunts in vulnerable patients identified by cerebral monitoring for ischemia. We compared transcranial cerebral oximetry (TCO) with carotid stump pressure measurements for selective shunt use.
We prospectively collected data on 300 consecutive patients operated on under general anesthesia between 2009 and 2016. Shunts were inserted for a 10% or greater drop in cerebral saturations and/or a mean stump pressure less than 40 mmHg.
Seventy-five patients, 25% of the study population, were shunted. The indication was a combined desaturation and stump pressure in 38 (50% of the shunted group), desaturation alone in 11 patients (15%), and a low stump pressure alone in 26 patients (35%). There were no significant differences in baseline characteristics between those patients who were or were not shunted, except angiographic collateral blood supply, which was more commonly identified in patients who were not shunted. A watershed infarct occurred in just one patient with borderline TCO and stump pressure measurements in whom a shunt was not used.
There was poor concordance between TCO and stump pressures, but using both in determining the need for shunt use almost eliminated cross-clamp ischemia in this series of 300 carotid endarterectomy patients.
在颈动脉内膜切除术过程中,可以通过脑监测来识别易发生缺血的脆弱患者,并使用颈动脉转流分流器来预防动脉夹闭缺血。我们比较了经颅氧饱和度(TCO)和颈动脉残端压力测量在选择性分流器使用中的作用。
我们前瞻性地收集了 2009 年至 2016 年间在全身麻醉下进行的 300 例连续患者的数据。分流器的插入指征是脑饱和度下降 10%以上和/或平均残端压力<40mmHg。
75 例患者(占研究人群的 25%)被分流。分流的指征是联合饱和度和残端压力降低的有 38 例(分流组的 50%),单纯饱和度降低的有 11 例(15%),单纯残端压力降低的有 26 例(35%)。除了在未分流的患者中更常见的血管造影侧支血液供应外,在那些被分流和未被分流的患者之间,没有显著的基线特征差异。只有一名患者的 TCO 和残端压力测量值接近临界值,未使用分流器,发生了分水岭梗死。
TCO 和残端压力之间的一致性较差,但在确定是否需要分流器使用时同时使用这两种方法,几乎可以消除本系列 300 例颈动脉内膜切除术患者的动脉夹闭缺血。