Michael M I, Hilmy A M, el-Domiaty N A, Wershana K
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1987;86(2):255-62. doi: 10.1016/0742-8413(87)90076-4.
Increase in serum transaminases (GOT and GPT) activity attributable to nitrite toxicity was observed in juvenile Clarias lazera after chronic exposure to nitrite. The application of SGOT and SGPT assays for monitoring the effect of nitrite exposure over a 6-month period has shown that changes in activities are correlated with histological effects in Clarias liver. Kidneys from fish exposed to nitrite were not noticeably different histologically from that of control fish. Hypertrophy and hyperplasia were the most consistent lesions that occurred in the gills. Lifting of lamellar epithelium and necrosis of some epithelial cells were also prominent.
在幼年革胡子鲶长期暴露于亚硝酸盐后，观察到血清转氨酶（谷草转氨酶和谷丙转氨酶）活性因亚硝酸盐毒性而增加。应用谷草转氨酶和谷丙转氨酶检测方法监测6个月内亚硝酸盐暴露的影响，结果表明酶活性变化与革胡子鲶肝脏的组织学效应相关。暴露于亚硝酸盐的鱼的肾脏在组织学上与对照鱼没有明显差异。鳃中出现的最一致的病变是肥大和增生。鳃小片上皮的隆起和一些上皮细胞的坏死也很明显。
