a Department of Neurology , Belfast Health and Social Care Trust , Belfast , Northern Ireland.
b Department of Neurology , Johns Hopkins School of Medicine , Baltimore , MD , USA.
Expert Rev Neurother. 2017 Oct;17(10):987-1002. doi: 10.1080/14737175.2017.1369880. Epub 2017 Sep 11.
Non-convulsive status epilepticus (NCSE) is a complex and diverse condition which is often an under-recognised entity in the intensive care unit. When NCSE is identified the optimal treatment strategy is not always clear. Areas covered: This review is based on a literature review of the key literature in the field over the last 5-10 years. The articles were selected based on their importance to the field by the authors. Expert commentary: This review discusses the complex situations when a neurological consultation may occur in a critical care setting and provides an update on the latest evidence regarding the recognition of NCSE and the decision making around determining the aggressiveness of treatment. It also considers the ictal-interictal continuum of conditions which may be met with, particularly in the era of continuous EEG, and provides an approach for dealing with these. Suggestions for how the field will develop are discussed.
非惊厥性癫痫持续状态(NCSE)是一种复杂且多样的病症,在重症监护病房中常常未被识别。当 NCSE 被识别时,最佳治疗策略并不总是明确的。
本综述基于过去 5-10 年该领域关键文献的文献回顾。作者根据其对该领域的重要性选择了这些文章。
本综述讨论了在重症监护环境中出现神经科会诊的复杂情况,并就 NCSE 的识别以及确定治疗积极性的决策方面的最新证据进行了更新。它还考虑了可能遇到的发作-发作间期连续状态,并提供了处理这些状态的方法。讨论了该领域的发展方向。