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The amino-acid sequences of sculpin islet somatostatin-28 and peptide YY.

作者信息

Cutfield S M, Carne A, Cutfield J F

出版信息

FEBS Lett. 1987 Apr 6;214(1):57-61. doi: 10.1016/0014-5793(87)80012-1.

DOI:10.1016/0014-5793(87)80012-1
PMID:2883025
Abstract

Two pancreatic peptides, somatostatin-28 and peptide YY, have been isolated from the Brockmann bodies of the teleost fish Cottus scorpius (daddy sculpin). Following purification by reverse-phase HPLC, each peptide was sequenced completely through to the carboxyl-terminus by gas-phase Edman degradation. Somatostatin-28 was the major form of somatostatin detected and is similar to the gene II product from anglerfish. Peptide YY (36 amino acids) more closely resembles porcine neuropeptide YY and intestinal peptide YY than it does the pancreatic polypeptides.

摘要

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