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杜父鱼胰岛中的第二种胰高血糖素。

A second glucagon in the pancreatic islets of the daddy sculpin Cottus scorpius.

作者信息

Cutfield S M, Cutfield J F

机构信息

Biochemistry Department, University of Otago, Dunedin, New Zealand.

出版信息

Gen Comp Endocrinol. 1993 Sep;91(3):281-6. doi: 10.1006/gcen.1993.1128.

DOI:10.1006/gcen.1993.1128
PMID:8224771
Abstract

The peptide hormone glucagon has been isolated from the islet tissue (Brockmann bodies) of the teleost Cottus scorpius (daddy sculpin) and sequenced. The sequence is HSEGTSNDYSKYLEDRKAQDFVQWLMNN differing at four positions from the glucagon found earlier in the same species by Conlon and coworkers (1987b, Eur. J. Biochem, 164, 117-122). Thus sculpin, in common with anglerfish, possesses two distinct glucagons. Comparative sequence data are presented as a phylogenetic tree.

摘要

已从鲉鱼(杜父鱼)的胰岛组织(布罗克曼体)中分离出肽激素胰高血糖素并对其进行了测序。其序列为HSEGTSNDYSKYLEDRKAQDFVQWLMNN,与康伦及其同事(1987b,《欧洲生物化学杂志》,164卷,117 - 122页)早些时候在同一物种中发现的胰高血糖素在四个位置上有所不同。因此,与安康鱼一样,杜父鱼也拥有两种不同的胰高血糖素。比较序列数据以系统发育树的形式呈现。

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