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X-linked immunodeficiency with hyperimmunoglobulinemia M appears to be linked to the DXS42 restriction fragment length polymorphism locus.

作者信息

Mensink E J, Thompson A, Sandkuyl L A, Kraakman M E, Schot J D, Espanol T, Schuurman R K

出版信息

Hum Genet. 1987 May;76(1):96-9. doi: 10.1007/BF00283057.

DOI:10.1007/BF00283057
PMID:2883112
Abstract

The gene involved in X-linked immunodeficiency with hyperimmunoglobulinemia M (XHM) was localized by the use of nine restriction fragment length polymorphic (RFLP) markers covering the entire X chromosome. Multipoint linkage analysis of RFLP data obtained in a three generation XHM pedigree indicates the Xq24-q27 area around the DXS42 RFLP locus as the most likely localization of the XHM locus.

摘要

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Mapping of the X linked form of hyper IgM syndrome (HIGM1).X连锁型高IgM综合征（HIGM1）的定位
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Genetic mapping of the human X chromosome by using restriction fragment length polymorphisms.利用限制性片段长度多态性对人类X染色体进行基因定位。
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Single-copy sequence hybridizes to polymorphic and homologous loci on human X and Y chromosomes.单拷贝序列与人类X和Y染色体上的多态性和同源基因座杂交。
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The genetic linkage map of the human X chromosome.人类X染色体的遗传连锁图谱。
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Mapping of a gene for X-linked agammaglobulinemia and evidence for genetic heterogeneity.X连锁无丙种球蛋白血症基因定位及遗传异质性证据
Hum Genet. 1986 Aug;73(4):327-32. doi: 10.1007/BF00279095.