Santos Lucielen Oliveira, Deamici Kricelle Mosquera, Menestrino Bruno Costa, Garda-Buffon Jaqueline, Costa Jorge Alberto Vieira
Laboratory of Biotechnology, Chemistry and Food School, Federal University of Rio Grande, Rio Grande, RS, Brazil.
Laboratory of Biochemical Engineering, Chemistry and Food School, Federal University of Rio Grande, Rio Grande, RS, Brazil.
World J Microbiol Biotechnol. 2017 Aug 22;33(9):169. doi: 10.1007/s11274-017-2332-4.
Static or modulated magnetic fields (MF) may interact with the biological system and affect the metabolism of microorganisms, such as their photosynthetic capacity or synthesis of carbohydrates. Their effects on microorganisms, which can be classified into inhibiting, stimulating and null, may be interpreted as the result of stress that cells undergo, thus, leading to responses through the same mechanisms. Biological effects of exposure to magnetic forces depend on magnetic intensity, frequency and exposure time. Modifications in these parameters may enhance product formation. Effects differ according to the form and application of MF characteristic parameters. Magnetic treatments have the advantages of being convenient and non-toxic, having low running cost, emitting no secondary pollution, enabling wide application and being easily shielded. MF application to the cultivation of microalgae, to improve the production of finished biomolecules, is a simple, inexpensive and powerful process. However, bioeffects of MF on microalgae need to be further investigated because there have currently been very few available reports in the literature. Thus, studies which aim at optimizing parameters involved in MF application must be developed in order to obtain the best conditions for the production of molecules with high economic potential.
静态或调制磁场（MF）可能与生物系统相互作用，并影响微生物的代谢，例如它们的光合能力或碳水化合物的合成。它们对微生物的影响可分为抑制、刺激和无影响，这些影响可被解释为细胞所经历的应激结果，从而通过相同机制引发反应。暴露于磁力的生物效应取决于磁场强度、频率和暴露时间。这些参数的改变可能会提高产物的形成。效应因MF特征参数的形式和应用而异。磁处理具有方便、无毒、运行成本低、不产生二次污染、应用广泛且易于屏蔽等优点。将MF应用于微藻培养以提高最终生物分子的产量是一个简单、廉价且有效的过程。然而，MF对微藻的生物效应需要进一步研究，因为目前文献中可用的报告非常少。因此，必须开展旨在优化MF应用相关参数的研究，以获得生产具有高经济潜力分子的最佳条件。
