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Balancing the Need for Personalization of QT Correction and Generalization of Study Results: Going Beyond Thorough QT Studies.

作者信息

Diemberger Igor, Raschi Emanuel, Trifirò Gianluca

机构信息

Department of Experimental, Diagnostic and Specialty Medicine, Institute of Cardiology, University of Bologna, Policlinico Sant'Orsola-Malpighi, Via Massarenti n. 9, 40138, Bologna, Italy.

Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.

出版信息

Clin Drug Investig. 2017 Oct;37(10):985-988. doi: 10.1007/s40261-017-0563-7.

DOI:10.1007/s40261-017-0563-7
PMID:28831689
Abstract
摘要

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The effects of gender on electrical therapies for the heart: physiology, epidemiology, and access to therapies.性别对心脏电疗的影响：生理学、流行病学和治疗方法的可及性。
Europace. 2017 Sep 1;19(9):1418-1426. doi: 10.1093/europace/eux068.
3
Use of azithromycin and risk of ventricular arrhythmia.
阿奇霉素的使用与室性心律失常风险
CMAJ. 2017 Apr 18;189(15):E560-E568. doi: 10.1503/cmaj.160355.
4
Drug-Induced Arrhythmia: Bridging the Gap Between Pathophysiological Knowledge and Clinical Practice.药物性心律失常：弥合病理生理知识与临床实践之间的差距
Drug Saf. 2017 Jun;40(6):461-464. doi: 10.1007/s40264-017-0529-y.
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Outcomes with Dronedarone in Atrial Fibrillation: What Differences Between Real-World Practice and Trials? A Meta-Analysis and Meta-Regression Analysis.决奈达隆治疗心房颤动的疗效：真实世界实践与试验之间有何差异？一项荟萃分析和元回归分析
Curr Pharm Des. 2017;23(6):944-951. doi: 10.2174/1381612822666161006141512.
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Evolution of strategies to improve preclinical cardiac safety testing.改善临床前心脏安全性测试策略的演变。
Nat Rev Drug Discov. 2016 Jul;15(7):457-71. doi: 10.1038/nrd.2015.34. Epub 2016 Feb 19.
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