Department of Paediatric Cardiology and General Paediatrics, 2nd Faculty of Medicine, Medical University of Warsaw, Warsaw, Poland
1st Chair and Department of Cardiology, 1st Faculty of Medicine, Medical University of Warsaw, Warsaw, Poland
Kardiol Pol. 2018;76(1):130-135. doi: 10.5603/KP.a2017.0166. Epub 2017 Aug 23.
Catheter ablation (CA) therapy is the first-choice treatment in adults with heart rhythm disturbances. Arrhythmias in adults are mainly conditioned by coronary artery disease. Aetiology of arrhythmias in children is mostly associated with inherited heart disorders. According to the current guidelines, CA is widely used in children, indicating the need to make it more achievable in the paediatric population.
To assess the efficacy and safety of CA in children with different types of arrhythmias on the initial learning curve at a newly built Ablation Centre in the Independent Paediatric Hospital of the Medical University of Warsaw, Poland.
The study population comprised 32 children with supraventricular tachycardias, asymptomatic pre-excitation syndrome, or ventricular ectopic beats undergoing CA. The mean age of the study population was 14.1 ± 2.4 years. In all patients, electrophysiological study (EPS) and CA were performed. Analysis with respect to procedure duration, fluoroscopy exposure duration, location of accessory pathways (AP), success rate, recurrences, and complications was performed.
The mean procedure duration was 105.4 ± 41.4 min (range 40-175 min). The mean fluoroscopy duration was 8:34 ± 5:01 min (range 1:28-21:01). The mean exposure to ionising radiation was 4.7 ± 3.2 mcG/kg. EPS revealed significantly more frequent presence of AP in the left side (57.1%). The radiofrequency ablation procedure was successful in 26 of 32 (81.3%) children, and cryoablation was successful in two of four patients. In two (6.3%) children minor complications occurred.
Catheter ablation may be effectively performed without major complications in the initial phase of the learning curve if a reasonable approach with a gradual increase of the procedural complexity is taken.
导管消融 (CA) 治疗是心律紊乱成人患者的首选治疗方法。成人的心律失常主要与冠状动脉疾病有关。儿童心律失常的病因主要与遗传性心脏病有关。根据现行指南,CA 在儿童中广泛应用,表明需要使其在儿科人群中更可行。
评估在波兰华沙医科大学独立儿童医院新建消融中心,对不同类型心律失常的儿童在初始学习曲线阶段进行 CA 的疗效和安全性。
研究人群包括 32 例接受 CA 治疗的室上性心动过速、无症状预激综合征或室性异位搏动的儿童。研究人群的平均年龄为 14.1 ± 2.4 岁。所有患者均进行电生理研究 (EPS) 和 CA。对手术持续时间、透视曝光持续时间、旁路 (AP) 位置、成功率、复发率和并发症进行分析。
平均手术持续时间为 105.4 ± 41.4 分钟(范围 40-175 分钟)。平均透视曝光时间为 8:34 ± 5:01 分钟(范围 1:28-21:01)。平均电离辐射暴露量为 4.7 ± 3.2 mcG/kg。EPS 显示 AP 更频繁地出现在左侧(57.1%)。32 例患儿中 26 例(81.3%)射频消融术成功,4 例患儿中 2 例(6.3%)冷冻消融术成功。2 例(6.3%)患儿出现轻微并发症。
如果采用合理的方法逐步增加手术复杂性,在学习曲线的初始阶段,导管消融可以有效地进行,且不会出现重大并发症。