Pereira Karine Gonçalves, Peres Marco Aurélio, Iop Débora, Boing Alexandra Crispim, Boing Antonio Fernando, Aziz Marina, d'Orsi Eleonora
Programa de Pós-graduação em Saúde Coletiva, Centro de Ciências da Saúde, Universidade Federal de Santa Catarina - Florianópolis (SC), Brasil.
Australian Research Centre for Population Oral Health, University of Adelaide - Adelaide, Australia.
Rev Bras Epidemiol. 2017 Apr-Jun;20(2):335-344. doi: 10.1590/1980-5497201700020013.
: To investigate polypharmacy among the elderly living in the urban area of Florianopolis, in the state of Santa Catarina, Brazil, estimating the prevalence and associated factors.
: This is a cross-sectional population-based study with a sample of 1,705 individuals aged 60 years old or older, between 2009 and 2010. The dependent variable was polypharmacy (defined as "use of five or more medications"). The following exploratory variables were utilized: sociodemographic data, use of health services and self-rated health status. Prevalence ratios (PR) were estimated by multivariate analysis using the Poisson regression.
: The mean for the medications used by the elderly population was 3.8 (ranging from 0 to 28). The prevalence of polypharmacy was 32%, with 95% confidence interval (95% CI) 29.8 - 34.3. The characteristics presenting a positive association with polypharmacy were: female gender (PR = 1.27; 95%CI 1.03 - 1.57), increasing age (PR = 1.38; 95% CI 1.08 - 1.77), negative self-rated health status (PR = 1.99; 95% CI 1.59 - 2.48) and medical appointments in the 3 months prior to the interview (PR = 1.89; 95% CI 1.53 - 2.32). The groups of medication most utilized by the elderly individuals in polypharmacy were those indicated for the cardiovascular system, digestive tract and metabolism, as well as the nervous system.
: The pattern of medication use among this elderly population is within the national average. The prevalence of polypharmacy and the characteristics associated with it were similar to those found in other regions of Brazil.
调查巴西圣卡塔琳娜州弗洛里亚诺波利斯市区老年人的多重用药情况，估计其患病率及相关因素。
这是一项基于人群的横断面研究，样本为2009年至2010年间1705名60岁及以上的个体。因变量为多重用药（定义为“使用五种或更多药物”）。使用了以下探索性变量：社会人口统计学数据、卫生服务利用情况和自我评估健康状况。采用泊松回归进行多变量分析估计患病率比（PR）。
老年人群使用药物的平均数为3.8（范围为0至28）。多重用药的患病率为32%，95%置信区间（95%CI）为29.8 - 34.3。与多重用药呈正相关的特征有：女性（PR = 1.27；95%CI 1.03 - 1.57）、年龄增长（PR = 1.38；95%CI 1.08 - 1.77）、自我评估健康状况较差（PR = 1.99；95%CI 1.59 - 2.48）以及在访谈前3个月内有医疗预约（PR = 1.89；95%CI 1.53 - 2.32）。多重用药的老年人最常使用的药物类别是用于心血管系统、消化道和新陈代谢以及神经系统的药物。
该老年人群的用药模式在全国平均水平范围内。多重用药的患病率及其相关特征与巴西其他地区的情况相似。
