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基于心血管健康评分的可改变生活方式与中国人群心房颤动患病率的关联

Association between modifiable lifestyle and the prevalence of atrial fibrillation in a Chinese population: Based on the cardiovascular health score.

作者信息

Yang Yiheng, Han Xu, Chen Yue, Gao Lianjun, Yin Xiaomeng, Li Huihua, Qiu Jing, Wang Youxin, Zhou Yong, Xia Yunlong

机构信息

Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, China.

Institute of Cardiovascular Diseases, First Affiliated Hospital of Dalian Medical University, Dalian, China.

出版信息

Clin Cardiol. 2017 Nov;40(11):1061-1067. doi: 10.1002/clc.22771. Epub 2017 Aug 21.

Abstract

BACKGROUND

The Cardiovascular Health (CVH) Score was comprised of a series of modifiable lifestyle and health factors, which was published by American Heart Association in 2010. Its relationship with atrial fibrillation (AF) remains unclear.

HYPOTHESIS

Individuals with a higher CVH Score had a lower risk of AF.

METHODS

Participants ≥40 years of age were recruited from the Jidong community. Information regarding the following 7 CVH metrics, including smoking, body mass index, diet, physical activity, total cholesterol, and fasting blood glucose, were collected. AF was confirmed with a standard 12-lead electrocardiography or based on the patients' medical histories. A multivariable logistic regression model was used to evaluate the relationship between ideal CVH and AF prevalence.

RESULTS

This study included 4477 individuals, among whom 48 had AF (1.07%). Overall, participants with higher ideal components scores had a lower risk of AF (odds ratio [OR]: 0.78; 95% confidence intervals [CI]: 0.62-0.97; P trend = 0.024). Subgroup analyses showed that the trend was consistent in the male participants ages 40 to 60 years. Moreover, patients with 5 to 7 ideal components or 3 to 4 ideal components were associated with 57% and 59% reduced risks for AF, respectively. We also detected a significant association between ideal health factors and the prevalence of AF (OR: 0.79; 95% CI: 0.68-0.93; P = 0.004).

CONCLUSIONS

Ideal health behavior and factors are associated with lower prevalence of AF in a community-based population. Improving healthy behavior and these factors may be beneficial to decrease the prevalence of AF.

摘要

背景

心血管健康(CVH)评分由一系列可改变的生活方式和健康因素组成,于2010年由美国心脏协会发布。其与心房颤动(AF)的关系仍不明确。

假设

CVH评分较高的个体患AF的风险较低。

方法

从冀东社区招募年龄≥40岁的参与者。收集以下7项CVH指标的信息,包括吸烟、体重指数、饮食、身体活动、总胆固醇和空腹血糖。通过标准12导联心电图或根据患者病史确诊AF。使用多变量逻辑回归模型评估理想CVH与AF患病率之间的关系。

结果

本研究纳入4477名个体,其中48人患有AF(1.07%)。总体而言,理想成分得分较高的参与者患AF的风险较低(优势比[OR]:0.78;95%置信区间[CI]:0.62-0.97;P趋势=0.024)。亚组分析表明,40至60岁男性参与者中的趋势一致。此外,具有5至7个理想成分或3至4个理想成分的患者患AF的风险分别降低57%和59%。我们还检测到理想健康因素与AF患病率之间存在显著关联(OR:0.79;95%CI:0.68-0.93;P = 0.004)。

结论

理想的健康行为和因素与社区人群中较低的AF患病率相关。改善健康行为和这些因素可能有助于降低AF的患病率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59fb/6490344/82269dcf448d/CLC-40-1061-g001.jpg

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