Dong Ying, Hao Guang, Wang Zengwu, Wang Xin, Chen Zuo, Zhang Linfeng
1 Division of Prevention and Community Health, National Center for Cardiovascular Disease, Fuwai Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, People's Republic of China.
2 Department of Epidemiology, School of Medicine, Jinan University, Guangzhou, People's Republic of China.
Angiology. 2019 Jul;70(6):523-529. doi: 10.1177/0003319718813448. Epub 2018 Nov 20.
We estimated the prevalence of ideal cardiovascular health (CVH), and its relationship with cardiovascular disease (CVD) and all-cause mortality in a Chinese population. A cross-sectional survey of CVD risk factors was conducted among Chinese participants aged 35 to 64 years in 2009 to 2010. In 2017, 8965 participants completed follow-up assessments in which CVD and all-cause mortality were collected; 8754 participants were eligible for analysis. The percentage of meeting all 7 ideal CVH metrics was 0.10%. During a median follow-up of 6.3 years, the incidence of CVD and all-cause mortality were 6.02% and 4.85% per 1000 person-year in participants with 0 to 1 ideal CVH metrics, 3.33% and 3.57% in those with 2 to 5, 0.40% and 0.79% in those with 6 to 7, respectively. After adjusting for covariates, the risk of CVD was significantly lower in participants with 2 to 5 (hazard ratio [HR]: 0.67, 95% confidence interval [CI]: 0.45-0.98) and 6 to 7 (HR: 0.12, 95%CI: 0.02-0.87) ideal CVH metrics compared to those with 0 to 1 ideal CVH metrics. The risk of all-cause mortality was decreased as ideal CVH metrics increased (HR: 0.78, 95%CI: 0.70-0.88). A greater number of ideal CVH metrics was associated with a lower risk of CVD and all-cause mortality, but the prevalence of all 7 ideal CVH metrics was low in a Chinese population.
我们估算了中国人群中理想心血管健康(CVH)的患病率,及其与心血管疾病(CVD)和全因死亡率的关系。2009年至2010年,我们对35至64岁的中国参与者进行了一项CVD危险因素的横断面调查。2017年,8965名参与者完成了随访评估,收集了CVD和全因死亡率数据;8754名参与者符合分析条件。符合全部7项理想CVH指标的比例为0.10%。在中位随访6.3年期间,具有0至1项理想CVH指标的参与者中,CVD发病率和全因死亡率分别为每1000人年6.02%和4.85%;具有2至5项指标的参与者中,分别为3.33%和3.57%;具有6至7项指标的参与者中,分别为0.40%和0.79%。调整协变量后,与具有0至1项理想CVH指标的参与者相比,具有2至5项(风险比[HR]:0.67,95%置信区间[CI]:0.45 - 0.98)和6至7项(HR:0.12,95%CI:0.02 - 0.87)理想CVH指标的参与者发生CVD的风险显著降低。全因死亡率风险随着理想CVH指标数量的增加而降低(HR:0.78,95%CI:0.70 - 0.