Bartholomew C, Saxinger W C, Clark J W, Gail M, Dudgeon A, Mahabir B, Hull-Drysdale B, Cleghorn F, Gallo R C, Blattner W A
JAMA. 1987 May 15;257(19):2604-8.
Risk for human T-cell lymphotropic virus type (HTLV-I) and human immunodeficiency virus (HIV) infection was evaluated in 100 homosexual or bisexual men from Trinidad. High seropositivity for HTLV-I (15% vs 2.4% in the general population) was linked to duration of homosexuality and numbers of partners, suggesting that HTLV-I, like HIV, can be transmitted by homosexual sex. Forty percent of homosexuals compared with 0.19% of the general population were seropositive for HIV, and sexual contact with US homosexual men and prior history of gonorrhea were major risk factors. The seroprevalence of HIV was three times higher than that for HTLV-I, suggesting that HIV is more efficiently transmitted, especially since HIV appears to have been recently introduced into Trinidad. Altered immune status was prominent in individuals infected with HIV and coinfected with HIV and HTLV-I. Whether HIV/HTLV-I coinfection amplifies clinical effects is a hypothesis that will require further evaluation.
对来自特立尼达的100名同性恋或双性恋男性进行了人类嗜T淋巴细胞病毒1型（HTLV-I）和人类免疫缺陷病毒（HIV）感染风险评估。HTLV-I的高血清阳性率（15%，而普通人群为2.4%）与同性恋持续时间和性伴侣数量有关，这表明HTLV-I与HIV一样，可通过同性性行为传播。40%的同性恋者HIV血清呈阳性，而普通人群中这一比例为0.19%，与美国同性恋男性的性接触和既往淋病病史是主要危险因素。HIV的血清流行率比HTLV-I高三倍，这表明HIV传播效率更高，特别是因为HIV似乎最近才传入特立尼达。免疫状态改变在感染HIV以及同时感染HIV和HTLV-I的个体中很突出。HIV/HTLV-I合并感染是否会放大临床效应是一个需要进一步评估的假设。
