Abdulkareem Abdullateef, D'Souza Ryan Steven, Patel Nitin, Donato Anthony A
Department of Internal Medicine, Reading Hospital and Medical Center, West Reading, Pennsylvania, USA.
Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota, USA.
BMJ Case Rep. 2017 Aug 23;2017:bcr-2017-221252. doi: 10.1136/bcr-2017-221252.
Pulmonary toxoplasmosis is a serious pulmonary condition caused by the protozoan It typically affects immunocompromised patients presenting acutely with cough, fever, myalgias, arthralgias and lymphadenopathy, and chronically with persistent cough and dyspnoea. Because of its protean features, it can mimic many more common lung conditions in the immunocompromised patient, including atypical pneumonia, pneumonia and interstitial lung disease. In this article, we present the case of a 55-year-old woman who presented to our hospital with persistent dyspnoea and cough, initially suspected to have an arthritis-related interstitial lung disease. She received a final diagnosis of pulmonary toxoplasmosis after lung biopsy demonstrated cysts, later confirmed by serology. Treatment with trimethoprim-sulfamethoxazole resulted in significant improvement of her respiratory symptoms after 3 months.
肺弓形虫病是一种由原生动物引起的严重肺部疾病。它通常影响免疫功能低下的患者，急性发作时表现为咳嗽、发热、肌痛、关节痛和淋巴结病，慢性发作时表现为持续咳嗽和呼吸困难。由于其症状多样，在免疫功能低下的患者中，它可以模仿许多更常见的肺部疾病，包括非典型肺炎、肺炎和间质性肺病。在本文中，我们介绍了一名55岁女性的病例，她因持续呼吸困难和咳嗽到我院就诊，最初怀疑患有与关节炎相关的间质性肺病。肺活检显示有囊肿后，她最终被诊断为肺弓形虫病，血清学检查后来证实了这一诊断。使用甲氧苄啶-磺胺甲恶唑治疗3个月后，她的呼吸道症状有了显著改善。
