Hôpitaux Universitaires, Maladies Infectieuses et Tropicales, Strasbourg, France
Université de Strasbourg, CHRU de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), VBP EA7290, Institut de Bactériologie, Strasbourg, France.
J Clin Microbiol. 2017 Nov;55(11):3167-3174. doi: 10.1128/JCM.00846-17. Epub 2017 Aug 23.
The implication of coagulase-negative staphylococci in human diseases is a major issue, particularly in hospital settings wherein these species often act as opportunistic pathogens. In addition, some coagulase-negative staphylococci such as have emerged as pathogenic bacteria, implicated in severe infections, particularly, osteoarticular infections, foreign-body-associated infections, bacteremia, and endocarditis. studies have shown the presence of several putative virulence factors such as adhesion factors, biofilm production, and proteolytic factors that might explain clinical manifestations. Taken together, the clinical and microbiological data might change the way clinicians and microbiologists look at in clinical samples.
凝固酶阴性葡萄球菌在人类疾病中的意义重大,尤其是在医院环境中,这些物种通常是机会致病菌。此外,一些凝固酶阴性葡萄球菌,如 ,已经成为致病菌,与严重感染有关,特别是骨关节炎感染、异物相关感染、菌血症和心内膜炎。研究表明,存在几种可能的毒力因子,如黏附因子、生物膜形成和蛋白水解因子,这可以解释临床表现。综上所述,临床和微生物学数据可能会改变临床医生和微生物学家看待临床样本中 的方式。