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and Cardiovascular Disease: A Story in Evolution.

作者信息

Bajaj Archna, Susztak Katalin, Damrauer Scott M

机构信息

From the Division of General Internal Medicine, Department of Medicine (A.B.), Renal Electrolyte and Hypertension Division, Department of Medicine (K.S.), Department of Genetics (K.S.), Division of Vascular Surgery, Department of Surgery (S.M.D.), University of Pennsylvania, Philadelphia; and Department of Surgery, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA (S.M.D.).

From the Division of General Internal Medicine, Department of Medicine (A.B.), Renal Electrolyte and Hypertension Division, Department of Medicine (K.S.), Department of Genetics (K.S.), Division of Vascular Surgery, Department of Surgery (S.M.D.), University of Pennsylvania, Philadelphia; and Department of Surgery, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA (S.M.D.)

出版信息

Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1587-1589. doi: 10.1161/ATVBAHA.117.309756.

DOI:10.1161/ATVBAHA.117.309756
PMID:28835482
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5657568/
Abstract
摘要

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2
Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice.足细胞中人类APOL1风险变异体的转基因表达可诱发小鼠肾病。
Nat Med. 2017 Apr;23(4):429-438. doi: 10.1038/nm.4287. Epub 2017 Feb 20.
3
Race, APOL1 Risk, and eGFR Decline in the General Population.普通人群中的种族、载脂蛋白L1风险与估算肾小球滤过率下降
J Am Soc Nephrol. 2016 Sep;27(9):2842-50. doi: 10.1681/ASN.2015070763. Epub 2016 Mar 10.
4
APOL1 Genotype, Kidney and Cardiovascular Disease, and Death in Older Adults.载脂蛋白L1基因型、肾脏与心血管疾病以及老年人死亡情况
Arterioscler Thromb Vasc Biol. 2016 Feb;36(2):398-403. doi: 10.1161/ATVBAHA.115.305970. Epub 2015 Dec 3.
5
Million Veteran Program: A mega-biobank to study genetic influences on health and disease.百万退伍军人计划:一个大型生物银行,用于研究遗传对健康和疾病的影响。
J Clin Epidemiol. 2016 Feb;70:214-23. doi: 10.1016/j.jclinepi.2015.09.016. Epub 2015 Oct 9.
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APOL1 Risk Variants Are Strongly Associated with HIV-Associated Nephropathy in Black South Africans.APOL1风险变异与南非黑人的HIV相关性肾病密切相关。
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