Wadee Reubina
Department of Anatomical Pathology, University of the Witwatersrand Medical School, Johannesburg, South Africa.
National Health Laboratory Service (NHLS), Johannesburg, South Africa.
SAGE Open Med Case Rep. 2017 Aug 9;5:2050313X17724060. doi: 10.1177/2050313X17724060. eCollection 2017.
Leiomyosarcomas of soft tissue are malignant tumours that are not infrequently encountered in clinical medicine and histopathology. Such sarcomas of the eye are, however, a rare occurrence.
Herein, the histopathological features of a case of conjunctival leiomyosarcoma are described. A 38-year-old HIV-positive male, who was otherwise fit and healthy, presented with redness of his right eye and a mass of the conjunctiva. Clinically, he did not have any soft-tissue masses elsewhere in the body.
He underwent monoblock excision of the conjunctival mass which was confirmed histologically to be a leiomyosarcoma. Unfortunately, the patient had not returned for follow-up examination.
The differential diagnosis of a conjunctival spindle cell neoplasm is broad. While a spindle cell carcinoma is the most likely tumour, other tumours must be borne in mind so as not to misdiagnose primary sarcomas in this unusual location.
软组织平滑肌肉瘤是临床医学和组织病理学中并不罕见的恶性肿瘤。然而,眼部的此类肉瘤却很少见。
本文描述了一例结膜平滑肌肉瘤的组织病理学特征。一名38岁的HIV阳性男性,身体状况良好,因右眼发红和结膜肿物就诊。临床上,他身体其他部位没有软组织肿物。
他接受了结膜肿物整块切除术,组织学检查证实为平滑肌肉瘤。不幸的是,患者未返回进行随访检查。
结膜梭形细胞肿瘤的鉴别诊断范围广泛。虽然梭形细胞癌是最可能的肿瘤,但必须考虑其他肿瘤,以免误诊这个不寻常部位的原发性肉瘤。