Narula Varsha, Siraj Fouzia, Bansal Anju
National Institute of Pathology, Indian Council of Medical Research, Delhi, India.
Can Urol Assoc J. 2015 Mar-Apr;9(3-4):E139-41. doi: 10.5489/cuaj.2396.
Primary renal sarcomas are exceptionally rare, constituting 1% of all malignant renal tumours. Since the prognosis for a renal sarcoma is particularly poor, differentiation from sarcomatoid renal cell carcinoma (RCC) is necessary. Histopathology and immunohistochemistry are the only modes of diagnosing these sarcomas as they have no specific features clinically and radiologically. We report a case of renal leiomyosarcoma which was clinically diagnosed as RCC. Histopathology revealed a spindle cell sarcoma and immunohistochemistry (IHC) confirmed a renal leiomyosarcoma. She also had a liver nodule and mass in the right side of neck and left arm. Biopsy from these sites revealed a similar morphology and IHC confirmed leiomyosarcoma. We report a case illustrating the rarity of this disease and its aggressive nature owing to fatal metastatic potential.
原发性肾肉瘤极为罕见，占所有肾恶性肿瘤的1%。由于肾肉瘤的预后特别差，因此有必要与肉瘤样肾细胞癌（RCC）进行鉴别。组织病理学和免疫组织化学是诊断这些肉瘤的唯一方法，因为它们在临床和放射学上没有特异性特征。我们报告一例临床上被诊断为RCC的肾平滑肌肉瘤病例。组织病理学显示为梭形细胞肉瘤，免疫组织化学（IHC）证实为肾平滑肌肉瘤。她还在肝脏、右侧颈部和左臂发现结节和肿块。这些部位的活检显示出相似的形态，IHC证实为平滑肌肉瘤。我们报告一例病例，说明这种疾病的罕见性及其因致命的转移潜能而具有的侵袭性。
