Lees Christoph, Ferrazzi Enrico
Imperial College London, London, UK.
Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, Imperial Healthcare NHS Trust, Du Cane Road, London, W12 0HS, UK.
Curr Hypertens Rep. 2017 Aug 23;19(9):76. doi: 10.1007/s11906-017-0766-6.
Blood pressure is a way of describing the end result of changes in cardiac output, intravascular volume and peripheral resistance. It has certain advantages in that it is a reproducible and easily measured parameter, but in itself, it offers only a limited understanding of the underlying haemodynamics. In pregnancy, profound haemodynamic changes occur and in hypertensive diseases of pregnancy defining a condition by blood pressure alone risks missing the underlying cause. Partly, this has been a problem of ascribing the cause of hypertensive syndromes to the placenta which has inhibited rigorous research into other possible causes of haemodynamic dysfunction. It is becoming increasingly evident that hypertension in pregnancy may be associated with primarily high cardiac output or high peripheral resistance. A knowledge of the underlying type of hypertension may allow more rational treatment of these conditions in pregnancy rather than therapeutic attempts at controlling blood pressure by any means possible as an end in itself.
血压是描述心输出量、血管内容量和外周阻力变化最终结果的一种方式。它具有一定优势，因为它是一个可重复且易于测量的参数，但就其本身而言，它对潜在血流动力学的理解有限。在妊娠期间，会发生深刻的血流动力学变化，在妊娠高血压疾病中，仅根据血压来定义一种情况可能会遗漏潜在病因。部分原因在于，一直以来将高血压综合征的病因归咎于胎盘，这阻碍了对血流动力学功能障碍其他可能原因的深入研究。越来越明显的是，妊娠期高血压可能主要与高心输出量或高外周阻力有关。了解潜在的高血压类型可能有助于在妊娠期间对这些情况进行更合理的治疗，而不是一味地试图通过任何可能的手段控制血压作为最终目的。
