胰腺癌生长的激素调控。
Hormonal control of pancreatic cancer growth.
作者信息
Liebow C, Hierowski M, duSapin K
出版信息
Pancreas. 1986;1(1):44-8. doi: 10.1097/00006676-198601000-00009.
Abstract
The effects of epidermal growth factor (EGF) and somatostatin-14 (SS) on growth of Mia PaCa-2 cells in cell culture were examined. EGF had no effect on cell growth in sera containing media but significantly increased growth in sera-free media. The effect of EGF was complete within 18 h. SS added with EGF entirely eliminated the growth stimulation of EGF. SS added to cells in culture with sera inhibited their growth as well.
摘要
研究了表皮生长因子（EGF）和生长抑素-14（SS）对细胞培养中Mia PaCa-2细胞生长的影响。在含血清培养基中，EGF对细胞生长无影响，但在无血清培养基中显著增加细胞生长。EGF的作用在18小时内完成。与EGF一起添加的SS完全消除了EGF的生长刺激作用。在含血清的培养物中添加到细胞中的SS也抑制了它们的生长。
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