Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, 229 Taibai Road, Xi'an 710069, China.
Honghui Hospital, Xi'an Jiaotong University, Xi'an 710054, China.
Molecules. 2017 Aug 24;22(9):1406. doi: 10.3390/molecules22091406.
This paper is intended to review advances in the botanical, phytochemical, traditional uses and pharmacological studies of the genus . Until now, 138 chemical constituents have been isolated and characterized from these plants, particularly from and . Among these compounds, lignans, triterpenoids, and flavonoids are the major bioactive constituents. Studies have shown that plants from the genus exhibit an extensive range of pharmacological properties both in vivo and in vitro, including anti-inflammatory, analgesic, antitumor, antiviral and antibacterial activities. In Traditional Chinese Medicine (TCM) culture, drugs that include stems have been used to cure rheumatism, gonarthritis, backache and pharyngitis, although there are few reports concerning the clinical use and toxicity of these plants. Further attention should be paid to gathering information about their toxicology data, quality-control measures, and the clinical value of the active compounds from genus .
本文旨在综述属植物的植物学、植物化学、传统用途和药理学研究进展。到目前为止,已经从这些植物,特别是从 和 中分离和鉴定了 138 种化学成分。在这些化合物中,木脂素、三萜类和黄酮类是主要的生物活性成分。研究表明,属植物在体内和体外均表现出广泛的药理活性,包括抗炎、镇痛、抗肿瘤、抗病毒和抗菌活性。在中医药文化中,包含 茎的药物被用于治疗风湿、关节炎、背痛和咽炎,尽管关于这些植物的临床用途和毒性的报道很少。应该进一步关注收集有关其毒理学数据、质量控制措施以及该属中活性化合物的临床价值的信息。