Allure Facial Laser Center and Medispa, Kirkland, Washington, USA; Department of Ophthalmology, University of Washington, Seattle, Washington, USA.
Department of Ophthalmology, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Surv Ophthalmol. 2018 May-Jun;63(3):381-388. doi: 10.1016/j.survophthal.2017.08.005. Epub 2017 Aug 31.
Ocular adnexal lymphoma and intraocular lymphoma, whether occurring simultaneously or sequentially, are often similar to associated systemic lymphoma. We describe 4 cases of ocular adnexal lymphoma or intraocular lymphoma with a dissimilar systemic lymphoma. Two of the cases represent Richter transformation of chronic lymphocytic leukemia/small-cell lymphoma into diffuse large B-cell lymphoma. In the third patient, conjunctival extranodal marginal zone lymphoma developed following treatment for Hodgkin lymphoma. The fourth patient had a remote history of systemic diffuse large B-cell lymphoma with a subsequent diagnosis of orbital extranodal marginal zone lymphoma. Clinical-pathological correlation is reported for all cases in addition to pertinent review of the literature.
眼附属器淋巴瘤和眼内淋巴瘤,无论是同时发生还是先后发生,通常与相关的系统性淋巴瘤相似。我们描述了 4 例眼附属器淋巴瘤或眼内淋巴瘤伴不同的系统性淋巴瘤。其中 2 例为慢性淋巴细胞白血病/小细胞淋巴瘤转化为弥漫性大 B 细胞淋巴瘤的里希特转化。第三例患者在霍奇金淋巴瘤治疗后发生结膜结外边缘区淋巴瘤。第四例患者有系统性弥漫性大 B 细胞淋巴瘤的既往病史,随后诊断为眼眶结外边缘区淋巴瘤。除了对文献的相关回顾外,我们还对所有病例进行了临床病理相关性报告。