多发性硬化症中的生长抑素。
Somatostatin in multiple sclerosis.
作者信息
Sørensen K V
出版信息
Acta Neurol Scand. 1987 Mar;75(3):161-7. doi: 10.1111/j.1600-0404.1987.tb07912.x.
Abstract
The detection of somatostatin, a 14 aminoacid peptide, in human brain and cerebrospinal fluid (CSF) initiated examinations by radioimmunoassay and immunocytochemical technique to elucidate its origin, localization, function, and possible significance in central nervous system disorders. The present survey deals with these aspects with special reference to multiple sclerosis (MS) and to correlation between disease activity and somatostatin content and variations in CSF.
摘要
在人脑中检测到由14个氨基酸组成的肽——生长抑素，随后通过放射免疫测定法和免疫细胞化学技术进行研究，以阐明其在中枢神经系统疾病中的起源、定位、功能及可能的意义。本综述探讨了这些方面，特别提及了多发性硬化症（MS）以及疾病活动与脑脊液中生长抑素含量及变化之间的相关性。
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