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生殖支原体:从基础科学到公共卫生——美国国立过敏与传染病研究所技术咨询结果总结及未来研究重点的共识建议

Mycoplasma genitalium From Basic Science to Public Health: Summary of the Results From a National Institute of Allergy and Infectious Disesases Technical Consultation and Consensus Recommendations for Future Research Priorities.

作者信息

Martin David H, Manhart Lisa E, Workowski Kimberly A

机构信息

Department of Epidemiology, Tulane University School of Public Health.

Department of Internal Medicine, Section of Infectious Diseases, Louisiana State University Health Sciences Center, New Orleans.

出版信息

J Infect Dis. 2017 Jul 15;216(suppl_2):S427-S430. doi: 10.1093/infdis/jix147.

Abstract

This article lays out the research priorities for Mycoplasma genitalium research agreed upon by the participants in a 2016 National Institutes of Allergy and Infectious Diseases-funded Technical Consultation focused on this organism. The state of current knowledge concerning the microbiology, epidemiology, clinical manifestations of infection, treatment, and public health significance of M. genitalium reviewed at the meeting is described in detail in the individual articles included in this supplemental edition of the Journal of Infectious Diseases. Here we summarize the points made in these articles most relevant to the formulation of the research priorities listed in this article. The most important recommendation resulting from this Technical Consultation is the initiation of clinical trials designed to determine definitively whether screening for and treatment of M. genitalium infections in women and their sexual partners improve reproductive health in women and/or prevent human immunodeficiency virus transmission.

摘要

本文阐述了2016年美国国立过敏与传染病研究所资助的、聚焦于生殖支原体的技术磋商会参与者们所达成的生殖支原体研究优先事项。会上所回顾的关于生殖支原体的微生物学、流行病学、感染临床表现、治疗以及公共卫生意义的现有知识,在《传染病杂志》增刊版所收录的各篇文章中有详细描述。在此,我们总结这些文章中与本文所列研究优先事项制定最为相关的要点。此次技术磋商会得出的最重要建议是启动临床试验,以明确确定对女性及其性伴侣进行生殖支原体感染筛查和治疗是否能改善女性生殖健康和/或预防人类免疫缺陷病毒传播。

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