Yu Jianwei, Zhou Yan, Luo Haodang, Su Xiaoling, Gan Tian, Wang Jingyun, Ye Zufeng, Deng Zhongliang, He Jun
Department of Public Health Laboratory Sciences, School of Public Health, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
The Affiliated Nanhua Hospital, Department of Clinical Laboratory, Hengyang Medical School, University of South China, Hengyang, China.
Front Microbiol. 2023 Feb 21;14:1098276. doi: 10.3389/fmicb.2023.1098276. eCollection 2023.
is a newly emerged sexually transmitted disease pathogen and an independent risk factor for female cervicitis and pelvic inflammatory disease. The clinical symptoms caused by infection are mild and easily ignored. If left untreated, can grow along the reproductive tract and cause salpingitis, leading to infertility and ectopic pregnancy. Additionally, infection in late pregnancy can increase the incidence of preterm birth. infections are often accompanied by co-infection with other sexually transmitted pathogens (, , and ) and viral infections (Human Papilloma Virus and Human Immunodeficiency Virus). A recent study suggested that plays a role in tumor development in the female reproductive system. However, few studies endorsed this finding. In recent years, has evolved into a new "superbug" due to the emergence of macrolide-and fluoroquinolone-resistant strains leading to frequent therapy failures. This review summarizes the pathogenic characteristics of and the female reproductive diseases caused by (cervicitis, pelvic inflammatory disease, ectopic pregnancy, infertility, premature birth, co-infection, reproductive tumors, etc.), as well as its potential relationship with reproductive tumors and clinical treatment.
是一种新出现的性传播疾病病原体，是女性宫颈炎和盆腔炎的独立危险因素。感染引起的临床症状轻微，容易被忽视。如果不治疗，它会沿生殖道生长并引起输卵管炎，导致不孕和异位妊娠。此外，妊娠晚期感染会增加早产的发生率。感染常伴有其他性传播病原体（如 、 、 ）和病毒感染（人乳头瘤病毒和人类免疫缺陷病毒）的合并感染。最近一项研究表明， 在女性生殖系统肿瘤发展中起作用。然而，很少有研究支持这一发现。近年来，由于大环内酯类和氟喹诺酮类耐药菌株的出现， 已演变成一种新的“超级细菌”，导致治疗失败频繁发生。本综述总结了 的致病特征以及由 引起的女性生殖疾病（宫颈炎、盆腔炎、异位妊娠、不孕、早产、合并感染、生殖系统肿瘤等），以及其与生殖系统肿瘤的潜在关系和临床治疗。
