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肾移植扭转后的长期移植物存活:快速诊断和手术管理是损伤可逆性的关键。

Long-term Graft Survival After Kidney Allograft Torsion: Rapid Diagnosis and Surgical Management Key to Reversibility of Injury.

作者信息

Serrano O K, Olowofela A S, Kandaswamy R, Riad S

机构信息

Division of Transplantation, Department of Surgery, University of Minnesota, Minneapolis, Minnesota, USA.

Division of Transplantation, Department of Surgery, University of Minnesota, Minneapolis, Minnesota, USA.

出版信息

Transplant Proc. 2017 Sep;49(7):1565-1569. doi: 10.1016/j.transproceed.2017.04.005.

Abstract

INTRODUCTION

Kidney allograft torsion (KAT) is a rare complication of kidney transplantation (KT) that occurs when the transplanted kidney rotates around its vascular pedicle, which may result in a catastrophic compromise of the graft's blood supply, deterioration of kidney function, and eventually premature graft death.

CASE REPORT

We report the case of a patient who had an acute kidney injury (AKI) episode from KAT. Her diagnosis was ascertained expeditiously and she had prompt surgical management. Five years after the KAT event, her baseline creatinine (Cr) stabilized around 1.6 mg/dL and she has achieved >8-year graft survival.

DISCUSSION

This case illustrates the reversibility of injury that can occur after a KAT event with a commensurate return to baseline kidney function when KAT is promptly diagnosed and treated. A high index of suspicion of this uncommon but catastrophic complication of KT must be maintained to achieve desirable long-term outcomes. A diagnosis of KAT must be considered when routine etiologies of an acute deterioration of kidney allograft function have been excluded. Finally, prophylactic nephropexy must be strongly considered with intraperitoneal placement of a kidney allograft to avoid KAT.

摘要

引言

肾移植扭转(KAT)是肾移植(KT)的一种罕见并发症,发生于移植肾围绕其血管蒂旋转时,这可能导致移植肾血供的灾难性损害、肾功能恶化,并最终导致移植肾过早死亡。

病例报告

我们报告一例因KAT发生急性肾损伤(AKI)发作的患者。她的诊断很快得以确定,并且她接受了及时的手术治疗。KAT事件发生五年后,她的基线肌酐(Cr)稳定在1.6mg/dL左右,并且移植肾存活已超过8年。

讨论

该病例表明,当KAT得到及时诊断和治疗时,KAT事件后发生的损伤具有可逆性,肾功能可相应恢复至基线水平。必须高度怀疑这种肾移植罕见但灾难性的并发症,以实现理想的长期预后。当排除肾移植功能急性恶化的常规病因时,必须考虑KAT的诊断。最后,对于腹腔内植入的肾移植,必须强烈考虑预防性肾固定术以避免KAT。

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