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肾移植和胰肾联合移植术后反复发生移植肾扭转:是否仍有可能挽救移植物?一例报告。

Recurrent Renal Allograft Torsion After Simultaneous Kidney and Pancreas Transplantation: Is it Still Possible to Salvage the Graft? A Case Report.

机构信息

Department of Surgery, Miami Transplant Institute, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, Florida.

Department of Medicine, Division of Transplant Nephrology, Miami Transplant Institute, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, Florida.

出版信息

Transplant Proc. 2021 Oct;53(8):2529-2535. doi: 10.1016/j.transproceed.2021.08.023. Epub 2021 Sep 2.

Abstract

BACKGROUND

Kidney allograft torsion (KAT) is defined as a rotation of the renal allograft around its vascular pedicle. It is a rare complication with high rate of graft loss. The nonspecific presentation and inability to provide a definitive diagnosis by imaging, mainly in cases of partial torsion, often delay the diagnosis and treatment. We report a case of recurrent complete torsion of the renal allograft after simultaneous kidney and pancreas transplantation, requiring 2 emergency exploratory laparotomies.

CASE REPORT

A 38-year-old woman with a history of intraperitoneal simultaneous kidney and pancreas transplantation underwent 2 separate emergency exploratory laparotomies secondary to complete renal allograft torsion, respectively, 7 and 11 months after the transplant. In both episodes, no adhesions were encountered. During the first operation, nephropexy was performed. During the second operation, an abdominal wall mesh was placed and fixed to the abdominal wall. Acute kidney injury related to KAT recovered in both occasions with a creatinine of 1.3 mg/dL at 4 months follow-up.

CONCLUSIONS

Renal torsion always should be suspected in intraperitoneally placed kidneys presenting with nonspecific symptoms, abdominal pain, oliguria, and worsening kidney function. Surgical exploration should be considered to salvage the renal graft. This case illustrates the reversibility of a severe injury related to this vascular complication with an adequate return to baseline kidney function even when diagnosis and surgical treatment of KAT might be delayed secondary to its misleading clinical presentation.

摘要

背景

肾移植扭转(KAT)定义为肾移植围绕其血管蒂的旋转。它是一种罕见的并发症,移植丢失率高。非特异性表现和影像学无法提供明确诊断,主要在部分扭转的情况下,常导致诊断和治疗延误。我们报告一例肾移植后同时发生的肾和胰腺移植后反复完全扭转的病例,需要进行 2 次紧急剖腹探查。

病例报告

一名 38 岁女性,有腹腔内同时进行肾和胰腺移植的病史,分别在移植后 7 个月和 11 个月因完全肾移植扭转而行 2 次单独的紧急剖腹探查。在这两个病例中均未发现粘连。第一次手术时进行了肾固定术。第二次手术时,放置了腹壁网片并固定在腹壁上。与 KAT 相关的急性肾损伤在两次手术中均得到恢复,随访 4 个月时肌酐为 1.3mg/dL。

结论

对于腹腔内放置的出现非特异性症状、腹痛、少尿和肾功能恶化的肾脏,应始终怀疑肾扭转。应考虑手术探查以挽救肾移植。该病例说明了这种血管并发症相关的严重损伤的可逆性,即使因误导性临床表现而延迟了 KAT 的诊断和手术治疗,也能使肾功能基本恢复正常。

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