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轮状病毒在吸收不良综合征中的持续存在:通过小肠活检免疫荧光法评估病毒与抗体滴度的关系。

Rotavirus persistence in malabsorption syndrome: virus assessment by immunofluorescence in small intestine biopsies in relation to antibody titres.

作者信息

Körting H J, Fiehring C, Senkpiel K, Körting L

出版信息

Acta Virol. 1987 Jan;31(1):31-5.

PMID:2883855
Abstract

Results of quantitative immunofluorescence (IF) in small intestine biopsies and the serum antibody titres as detected by indirect Rotalex test in rotavirus infections were compared using regression and correlation analysis. Based on the significance of the statistically established correlation (r = 0.76; n = 30) between immunohistological identification of rotavirus antigen and determination of serum antibody levels, the indirect Rotalex test may be applied as a diagnostic tool to avoid biopsies in productive rotavirus persistence.

摘要

运用回归分析和相关性分析,比较了轮状病毒感染时小肠活检组织定量免疫荧光(IF)结果与间接Rotalex试验检测的血清抗体滴度。基于轮状病毒抗原的免疫组织学鉴定与血清抗体水平测定之间统计学上确定的显著相关性(r = 0.76;n = 30),间接Rotalex试验可用作诊断工具,以避免在轮状病毒持续感染期进行活检。

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