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巴西绝经后骨质疏松症诊断与治疗指南。

Brazilian guidelines for the diagnosis and treatment of postmenopausal osteoporosis.

作者信息

Radominski Sebastião Cézar, Bernardo Wanderley, Paula Ana Patrícia de, Albergaria Ben-Hur, Moreira Caio, Fernandes Cesar Eduardo, Castro Charlles H M, Zerbini Cristiano Augusto de Freitas, Domiciano Diogo S, Mendonça Laura M C, Pompei Luciano de Melo, Bezerra Mailze Campos, Loures Marco Antônio R, Wender Maria Celeste Osório, Lazaretti-Castro Marise, Pereira Rosa M R, Maeda Sergio Setsuo, Szejnfeld Vera Lúcia, Borba Victoria Z C

机构信息

Universidade Federal do Paraná (UFPR), Curitiba, PR, Brazil.

Associação Médica Brasileira (AMB), Projeto Diretrizes, São Paulo, SP, Brazil.

出版信息

Rev Bras Reumatol Engl Ed. 2017;57 Suppl 2:452-466. doi: 10.1016/j.rbre.2017.07.001. Epub 2017 Aug 21.

DOI:10.1016/j.rbre.2017.07.001
PMID:28838768
Abstract

Osteoporosis is the leading cause of fractures in the population older than 50 years. This silent disease affects primarily postmenopausal women and the elderly, and the morbidity and mortality rates are high. The main goal of treating osteoporosis is the prevention of fractures. The identification of populations at risk through early diagnosis and treatment is essential. The last Brazilian guideline for the treatment of postmenopausal osteoporosis was elaborated in 2002. Since then, new strategies for diagnosis and risk stratification have been developed, and drugs with novel action mechanisms have been added to the therapeutic arsenal. The Osteoporosis and Osteometabolic Diseases Committee of the Brazilian Society of Rheumatology, in conjunction with the Brazilian Medical Association and other Societies, has developed this update of the guidelines for the treatment of postmenopausal osteoporosis according to the best scientific evidence available. This update is intended for professionals in many medical and health specialties involved in the treatment of osteoporosis, for physicians in general and for health-related organizations.

摘要

骨质疏松症是50岁以上人群骨折的主要原因。这种隐匿性疾病主要影响绝经后女性和老年人,其发病率和死亡率都很高。治疗骨质疏松症的主要目标是预防骨折。通过早期诊断和治疗来识别高危人群至关重要。巴西上一版绝经后骨质疏松症治疗指南于2002年制定。自那时以来,已开发出新的诊断和风险分层策略,治疗药物库中也增加了具有新作用机制的药物。巴西风湿病学会骨质疏松症和骨代谢疾病委员会与巴西医学协会及其他学会合作,根据现有最佳科学证据制定了本版绝经后骨质疏松症治疗指南更新版。本更新版面向参与骨质疏松症治疗的许多医学和健康专业的专业人员、普通医生以及与健康相关的组织。

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