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血管性认知障碍:进展与趋势。

Vascular cognitive impairment: Advances and trends.

机构信息

Department of neurology and laboratory of functional neurosciences and diseases, Amiens university medical center, CHU Nord, 80054 Amiens cedex, France.

Department of neurology and laboratory of functional neurosciences and diseases, Amiens university medical center, CHU Nord, 80054 Amiens cedex, France.

出版信息

Rev Neurol (Paris). 2017 Jul-Aug;173(7-8):473-480. doi: 10.1016/j.neurol.2017.06.009. Epub 2017 Aug 31.

Abstract

The presence of vascular neurocognitive impairment (whatever the severity) is always associated with a functional impact and increased risk of dependency and institutionalization. However, vascular cognitive impairment remains underdiagnosed, and the mechanisms underlying post-stroke cognitive disorders are still poorly understood. However, the advent of new criteria and a standardized international neuropsychological battery is expected to lead to improved diagnosis and management, and the development of novel techniques (such as brain imaging and amyloid PET) should improve our understanding of the mechanisms underlying vascular cognitive impairment and help to identify potential targets for therapy.

摘要

血管性认知功能障碍(无论严重程度如何)的存在总是与功能影响以及依赖性和住院风险增加相关。然而,血管性认知障碍的诊断仍然不足,中风后认知障碍的机制仍知之甚少。然而,新的标准和标准化的国际神经心理学测试工具的出现有望改善诊断和管理,而新型技术(如脑成像和淀粉样 PET)的发展应有助于我们更好地了解血管性认知障碍的机制,并有助于确定潜在的治疗靶点。

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