DeMaria Andrea L, Sundstrom Beth, Moxley Grace E, Banks Kendall, Bishop Ashlan, Rathbun Lesley
College of Health and Human Sciences, Purdue University, West Lafayette, IN, USA.
Department of Communication, College of Charleston, Charleston, SC, USA.
Women Birth. 2018 Apr;31(2):e99-e104. doi: 10.1016/j.wombi.2017.08.001. Epub 2017 Aug 31.
To describe birthing outcomes among women who consumed castor oil cocktail as part of a freestanding birth center labor induction protocol.
De-identified data from birth logs and electronic medical records were entered into SPSS Statistics 22.0 for analysis for all women who received the castor oil cocktail (n=323) to induce labor between January 2008 and May 2015 at a birth center in the United States. Descriptive statistics were analyzed for trends in safety and birthing outcomes.
Of the women who utilized the castor oil cocktail to stimulate labor, 293 (90.7%) birthed vaginally at the birth center or hospital. The incidence of maternal adverse effects (e.g., nausea, vomiting, extreme diarrhea) was less than 7%, and adverse effects of any kind were reported in less than 15% of births. An independent sample t-test revealed that parous women were more likely to birth vaginally at the birth center after using the castor oil cocktail than their nulliparous counterparts (p<.010), while gestational age (p=.26), woman's age (p=.23), and body mass index (p=.28) were not significantly associated.
Nearly 91% of women in the study who consumed the castor oil cocktail to induce labor were able to give birth vaginally with little to no maternal or fetal complications. Findings indicate further research is needed to compare the safety and effectiveness of natural labor induction methodologies, including castor oil, to commonly used labor induction techniques in a prospective study or clinical trial.
描述将蓖麻油混合剂作为独立分娩中心引产方案一部分的女性的分娩结局。
将来自出生记录和电子病历的去识别化数据录入SPSS Statistics 22.0,对2008年1月至2015年5月在美国一家分娩中心接受蓖麻油混合剂引产的所有女性(n = 323)进行分析。对安全性和分娩结局趋势进行描述性统计分析。
使用蓖麻油混合剂引产的女性中,293例(90.7%)在分娩中心或医院经阴道分娩。产妇不良反应(如恶心、呕吐、严重腹泻)的发生率低于7%,任何类型的不良反应在分娩中报告的比例不到15%。独立样本t检验显示,经产妇在使用蓖麻油混合剂后比初产妇更有可能在分娩中心经阴道分娩(p <.010),而孕周(p =.26)、产妇年龄(p =.23)和体重指数(p =.28)无显著相关性。
本研究中近91%使用蓖麻油混合剂引产的女性能够经阴道分娩,几乎没有产妇或胎儿并发症。研究结果表明,需要进一步研究,以前瞻性研究或临床试验的方式比较包括蓖麻油在内的自然引产方法与常用引产技术的安全性和有效性。