结直肠癌检测：是时候摒弃钡灌肠了吗？
Colorectal cancer detection: time to abandon barium enema?
作者信息
Shariff M K, Sheikh K, Carroll N R, Whitley S, Greenberg D, Parkes M, Cameron E A B
机构信息
Department of Gastroenterology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
出版信息
Frontline Gastroenterol. 2011 Apr;2(2):105-109. doi: 10.1136/fg.2010.003616. Epub 2011 Jan 19.
OBJECTIVES
To assess the sensitivity of double contrast barium enema (DCBE) for diagnosing colorectal cancer (CRC).
DESIGN
Retrospective evaluation of DCBE performed in the 2 years prior to diagnosis of CRC.
SETTING
Teaching hospital in Cambridge, UK.
PATIENTS
1310 consecutive cases of CRC identified from cancer registry data.
INTERVENTIONS
DCBE and colonoscopy.
MAIN OUTCOME MEASURES
Sensitivity of DCBE for diagnosing CRC.
RESULTS
215 patients had undergone a DCBE within the 2 years prior to diagnosis with CRC. After excluding those reported as inadequate, 37 of these were reported as normal, giving a sensitivity of 83% (81-85%).
CONCLUSIONS
The performance of DCBE is inadequate for the exclusion of CRC. Expansion of colonoscopy and CT colonography capacity is urgently required nationally so that DCBE can finally be abandoned as a firstline test in patients at risk of CRC.
目的
评估双重对比钡剂灌肠（DCBE）诊断结直肠癌（CRC）的敏感性。
设计
对CRC诊断前2年内进行的DCBE进行回顾性评估。
地点
英国剑桥的教学医院。
患者
从癌症登记数据中确定的1310例连续CRC病例。
干预措施
DCBE和结肠镜检查。
主要观察指标
DCBE诊断CRC的敏感性。
结果
215例患者在CRC诊断前2年内接受了DCBE检查。排除报告为不充分的病例后，其中37例报告为正常，敏感性为83%（81%-85%）。
结论
DCBE排除CRC的性能不足。国家迫切需要扩大结肠镜检查和CT结肠成像的能力，以便最终能够放弃将DCBE作为CRC高危患者的一线检查。
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