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使用扫描电子显微镜对胆结石溶解进行的体外研究。

In vitro studies of gallstone dissolution using the scanning electron microscope.

作者信息

Burnett W, Dwyer K R, Kennard C H, Roberts G

出版信息

Aust N Z J Surg. 1979 Feb;49(1):131-3. doi: 10.1111/j.1445-2197.1979.tb06460.x.

DOI:10.1111/j.1445-2197.1979.tb06460.x
PMID:288418
Abstract

Scanning electron microscope studies on cholesterol gallstones, which had been subjected to, but had not been completely dissolved by, chenodeoxycholate and deoxycholate salts, have indicated the presence of an insoluble organic matrix, probably a mucopolysaccharide. Solution of a gallstone in vitro is enhanced by the addition of heparin which dissolved this matrix, thus allowing complete dissolution of cholesterol in a gallstone.

摘要

对经鹅去氧胆酸盐和脱氧胆酸盐处理但未完全溶解的胆固醇胆结石进行扫描电子显微镜研究表明,存在一种不溶性有机基质,可能是一种粘多糖。体外添加肝素可增强胆结石的溶解,肝素能溶解这种基质,从而使胆结石中的胆固醇完全溶解。

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